An electrical engineer and senior editor for Aviation Week and Space Technology, Philip Klass began investigating UFOs in 1966 after participating in a panel discussion on the subject for the Institute of Electrical and Electronics Engineers (IEEE). From that time forward Klass has investigated UFO sightings in an effort to find a credible prosaic explanation, and became one of the most widely recognized UFO "debunkers." A founding member of the Committee for the Scientific Investigation of Claims of the Paranormal (CSICOP), serving on the Executive Council and the UFO subcommittee, Klass has authored seven books and numerous articles on UFOs, including the Skeptics UFO Newsletter in 1989. In the early 1970s, he became interested in space based weapons, and began collecting material related to the Strategic Defense Initiative (SDI) for a possible book. The Klass Collection relate to his forty-plus years of investigating UFO sightings, and includes correspondence with many of the leading UFOlogists, both pro and con. The collection contains case files, subject files, and correspondence. In addition, Klass' SDI material is included.

The James V. Neel Papers document nearly every phase of the career of one of the founders of human population genetics in the United States. Neel was particularly thorough and organized, and retained virtually all of his significant scientific correspondence, committee reports, minutes of meetings, and drafts of manuscripts. The collection also includes data collected during Neel's work among the Xavante, Yanomanö and other indigenous populations. In a career that spanned the period from the late work of Thomas Hunt Morgan and Charles B. Davenport to the contemporary world of molecular genetics and nucleic acids, Neel knew, worked with, and corresponded with many of the most influential 20th century practitioners of genetics. The collection begins in earnest in 1943, after Neel had decided to focus on human genetics. Neel's work with Drosophila and none of his Drosophila manuscripts are found in the collection.